Ursodeoxycholic Acid: From Dissolution of Gallstones to Lipid-Lowering Agent
نویسندگان
چکیده
منابع مشابه
Ursodeoxycholic acid dissolution of gallstones in cystic fibrosis.
The dissolution of cholesterol gall stones is documented in two adults with cystic fibrosis. Improved care of patients with cystic fibrosis has meant that most survive into adult life. Consequently extrathoracic complications are assuming greater importance, especially those of the hepatobiliary system. These include progressive biliary cirrhosis (25%) leading to portal hypertension and oesopha...
متن کاملFormulation and Evaluation of Nanocrystals of a Lipid Lowering Agent
Atorvastatin calcium, the lipid lowering agent, is taken as a model drug characterized by poor water solubility and bioavailability. In this study an attempt was made for preparation of nanocrystals using high pressure homogenization. A number of stabilizers were included as well as polymers at different concentrations, and the formulations were homogenized for ten cycles at a pressure of 1000 ...
متن کاملFormulation and Evaluation of Nanocrystals of a Lipid Lowering Agent
Atorvastatin calcium, the lipid lowering agent, is taken as a model drug characterized by poor water solubility and bioavailability. In this study an attempt was made for preparation of nanocrystals using high pressure homogenization. A number of stabilizers were included as well as polymers at different concentrations, and the formulations were homogenized for ten cycles at a pressure of 1000 ...
متن کاملEffect of Ursodeoxycholic Acid Alone and Ursodeoxycholic Acid Plus Domperidone on Radiolucent Gallstones and Gallbladder Contractility in Humans
Background/Aims. The aim of this study was to compare the effects of ursodeoxycholic acid (UDCA) alone and UDCA plus domperidone on dissolution of solitary or multiple gallstones. Methods. Fifty-three patients with cholesterol gallstones were randomized into three treatment groups: group I (n = 22) was given UDCA (15 mg/kg/day) alone and group II (n = 18) was treated with domperidone (30 mg/day...
متن کاملformulation and evaluation of nanocrystals of a lipid lowering agent
atorvastatin calcium, the lipid lowering agent, is taken as a model drug characterized by poor water solubility and bioavailability. in this study an attempt was made for preparation of nanocrystals using high pressure homogenization. a number of stabilizers were included as well as polymers at different concentrations, and the formulations were homogenized for ten cycles at a pressure of 1000 ...
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ژورنال
عنوان ژورنال: Mayo Clinic Proceedings
سال: 1994
ISSN: 0025-6196
DOI: 10.1016/s0025-6196(12)61834-5